Purpose This study aimed to identify the relationships among clinical nurses’ second victim experience following patient safety incidents, individual and organizational support, job satisfaction, and turnover intention, and to examine the factors influencing turnover intention. Methods: A cross-sectional survey was conducted using a convenience sample of 187 clinical nurses from a general hospital who had been employed for more than 6 months and had either directly or indirectly experienced patient safety incidents. Data were collected using a self-report questionnaire. The collected data were analyzed using descriptive statistics, independent t-tests, one-way analysis of variance, the Scheffé test, Pearson correlation coefficients, and multiple regression analysis. Results: The mean scores for second victim experience, individual support, organizational support, job satisfaction, and turnover intention were 3.12, 3.94, 2.79, 3.05, and 3.87, respectively. The factors influencing turnover intention were organizational support (β=-.21, p=.042), job satisfaction (β=-.20, p=.047), and second victim experience (β=.14, p=.049). Conclusion: To alleviate clinical nurses’ turnover intention, it is necessary to implement strategies that reduce second victim experience and enhance organizational support and job satisfaction. In particular, hospital managers should recognize nurses’ second victim experience and make efforts to strengthen emotional care and establish organizational support systems for nurses following patient safety incidents.