Purpose This study explored and characterized the interpersonal conflict experiences among mid-career nurses working together. Methods Data were collected from May 2021 to February 2022 through individual in-depth interviews of eight mid-career nurses with conflict experience among nurse colleagues in their work place. The transcribed data were analyzed using Colaizzi's phenomenological method. Results Four categories were identified: experiencing discomfort in relationships as reverse discrimination; bearing the heavy burden of being pushed up and down; adopting self-rescue measures to cope with the current situation; and navigating a workplace where resignation and expectation coexist. Conclusion This study provided an in-depth exploration of interpersonal conflict experiences among mid-career nurses’ working together. Thus, shedding light on the need for proactive educational and policy initiatives to effectively manage and mitigate such conflicts among nurse colleagues in this career stage.